Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Associated With IgM Paraprotein: A Clinicopathologic Study of 26 Cases
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چکیده
منابع مشابه
Small lymphocytic lymphoma: a clinicopathologic analysis of 268 cases.
We analyzed specimens from 268 patients with small lymphocytic lymphoma (SL) to identify prognostic factors significant for survival. These patients were staged and treated according to the protocols of the Cancer and Leukemia Group B, Eastern Cooperative Oncology Group, Southeastern Cancer Study Group, and the Southwest Oncology Group. Univariate analysis showed that a large-cell grade greater...
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Transformation to a large cell lymphoma may occur during the course of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) in approximately 5% of the cases. This is known as Richter's transformation. A much less frequent transformation to Hodgkin lymphoma may occur. We report a case of CLL/SLL in which a transformation to Hodgkin lymphoma occurred, and we review previously publish...
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1. Reiter A, Schrappe M, Luwdig WD, et al. Chemotherapy in 998 unselected childhood acute lymphoblastic leukemia patients. Results and conclusions of the multicenter trial ALL-BFM 86. Blood 1994; 84:3122-33. 2. Wan JH, Trainor KJ, Brisco MJ, Morley AA. Monoclonality in B-cell lymphoma detected in paraffin wax embedded using the polymerase chain reaction. J Clin Pathol 1990; 43:888-90. 3. Brisco...
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We studied 7 cases of large cell transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) immunophenotyped by multiparameter flow cytometry. The 6 women and 1 man ranged in age from 45 to 91 years. All had previous or concurrent evidence of CLL/SLL. Morphologic features and sites of involvement of the diffuse large B-cell lymphoma (DLBCL) were heterogeneous; 2 cases h...
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A 39-year-old man noted a pigmented lesion on his back that had been growing for ;1 year. A punch biopsy demonstrated malignant melanoma, nodular type. He was also found to have a white blood cell count of 45.8 3 10/mL and palpable axillary, cervical, and inguinal lymph nodes. The blood was sent for flow cytometry and demonstrated a population of small CD19 B cells that were l light chain restr...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2005
ISSN: 0002-9173
DOI: 10.1309/fdgw-b5c2-myry-xh2e